“Metabolic surgery in Asian patients with type 2 diabetes mellitus and body mass index less than 30kg/m2: A systematic review”

“Metabolic surgery in Asian patients with type 2 diabetes mellitus and body mass index less than 30kg/m2: A systematic review”

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Background: The effect of metabolic surgery on long-term diabetes remission in Asian patients with a body mass index (BMI) < 30 kg/m2 has not been widely reported.Methods: We conducted a systematic review of the PubMed and Cochrane Library databases from inception to June 2024.All clinical flex 4 heartworm test trials and observational studies involving the effect of metabolic surgery in Asian patients with type 2 diabetes mellitus and BMI <30 kg/m2 were considered.

The quality of the studies was assessed using the Newcastle-Ottawa scale.Results: Of the 1175 studies screened, 21 studies (11 prospective and 10 retrospective), including 1005 patients, were selected.Only one study had a control group.

The longest follow-up was 60 months.The results showed significant improvement in glycated hemoglobin (HbA1c), fasting blood glucose (FBG), 2-h plasma glucose (2hPG), homeostasis model assessment for insulin resistance index (HOMA-IR), fasting C-peptide, triglycerides, total cholesterol, and a reduction in the use of oral hypoglycemic agents/insulin at 12, 24, 36, and 60 months after metabolic surgery.The most common surgical complications observed were anemia (2.

1 %–33 %), marginal ulcer (4.2 %–17.3 %), gastrointestinal bleeding (1.

9 %–12 %), anastomotic leak (2.1 %–3.5 %), anastomotic stenosis (2.

1 %–3.5 %), reoperation (1.18 %), and a mortality rate of zero.

Conclusions: Long-term diabetes remission, along with improvements in HbA1c, 2hPG, FBG, and HOMA-IR, with an acceptable rate of complications, was observed in Asian patients with BMI <30 kg/m2 after metabolic surgery.Future research houston texans shorts with controlled studies should focus on preoperative patient selection criteria beyond just the BMI cutoff.